CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY: UPDATE ON DIAGNOSIS AND TREATMENT

Jin Jun Luo, MD, PhD, MHA; Xiaohong Si, MD, PhD

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a condition that presents with progressive or relapsing motor and sensory dysfunction, primarily affecting older adults and men. The document discusses the immunopathogenesis of CIDP, which involves both cellular and humoral mechanisms, and highlights the importance of accurate diagnosis, particularly in atypical cases. It reviews first-line treatments such as corticosteroids, intravenous immunoglobulin, and plasma exchange, as well as newer therapies like the FDA-approved FcRn antagonist for refractory cases. The document emphasizes the need for individualized management to improve patient outcomes.