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Brigham and Women’s Hospital, Boston; University of California San Diego School of Medicine, La Jolla
Rheumatoid arthritis is a prevalent immune-mediated disease characterized by inflammatory arthritis, primarily affecting the small joints of the hands and feet. The disease manifests as a continuum, beginning with asymptomatic immune dysfunction and progressing to clinically apparent arthritis. This review emphasizes seropositive rheumatoid arthritis, marked by the presence of specific autoantibodies, and discusses the implications of these findings for treatment and management.
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