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Clinical reviews
PREHOSPITAL TRANEXAMIC ACID FOR SEVERE TRAUMA
The PATCH-Trauma Investigators and the ANZICS Clinical Trials Group
PDF202310 pages610 KB
The study randomly assigned adults with major trauma to receive either tranexamic acid or a placebo before hospital admission. The primary outcome measured was survival with a favorable functional outcome at 6 months post-injury, assessed using the Glasgow Outcome Scale-Extended. The trial involved 1310 patients across multiple emergency medical services in Australia, New Zealand, and Germany, aiming to determine the efficacy of tranexamic acid in improving survival rates in severe trauma cases.
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