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Clinical reviews
CLINICAL AND BACTERIOLOGICAL EFFECTIVENESS OF THREE DIFFERENT SHORT-COURSE ANTIBIOTIC REGIMENS AND SINGLE-DOSE FOSFOMYCIN FOR UNCOMPLICATED LOWER URINARY TRACT INFECTIONS IN WOMEN (SCOUT): A PRAGMATIC, MULTICENTRE, OPEN-LABEL, RANDOMISED CLINICAL TRIAL
Carl Llor, Ramon Monfà, Ana Garcia-Sangenís, Alfonso Leiva, Jaime Marín-Cañada, María Antonia Sánchez-Calavera, Ana Moragas, Mercedes Aguilar-Sánchez, Amelia Troncoso-Mariño, Ricardo Rodríguez-Barrientos, José M Molero, Dan Ouchi, Cristina
PDF202411 pages550 KB
The research was conducted as a phase 4, pragmatic, multicentre, parallel-group, open-label, randomised clinical trial in Spanish primary care centres from 2022 to 2024. It involved women aged 18 years or older with at least one UTI-specific symptom and a positive urine dipstick test. The primary outcome was the proportion of patients with clinical resolution at day 7, comparing four different treatment regimens for uncomplicated urinary tract infections.
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