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Clinical reviews
ANTI‑OBESITY MEDICATIONS IN CHILDREN AND ADOLESCENTS: BLOOD PRESSURE AND CHRONIC KIDNEY DISEASE IMPLICATIONS
Margaret A. Clement, Joyce P. Samuel
PDF202613 pages882 KB
Pediatric obesity is a growing public health crisis with profound cardiometabolic and kidney consequences extending into adulthood. The review emphasizes the need for integrated treatment approaches, highlighting the efficacy of lifestyle interventions and pharmacotherapy. It discusses the approval of five medications for non-syndromic obesity in children, with glucagon-like peptide-1 receptor agonists and combination phentermine/topiramate showing the greatest efficacy. The review also addresses barriers to effective treatment, including access and sustainability issues.
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