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Department of Pediatrics, University of Alberta; Alberta Health Services; John W. Scott Health Sciences Library, University of Alberta
The review synthesizes data from 11 studies focused on preterm infants, particularly those born at less than 30 weeks of gestation. It highlights the potential of low SVC flow as a surrogate marker for systemic blood flow and its implications for neonatal health. The studies included in the review were assessed for bias, revealing significant clinical heterogeneity and challenges in comparability among study groups. The findings suggest that low SVC flow may be linked to adverse outcomes such as intraventricular hemorrhage and long-term neurodevelopmental challenges.
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