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Clinical reviews
SYNDROME OF INAPPROPRIATE ANTIDIURESIS: FROM PATHOPHYSIOLOGY TO MANAGEMENT
Department of Medicine, University of Melbourne; Department of Endocrinology, The Austin Hospital; Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel; Department of Clinical Research, University of Basel
PDF102 pages3.6 MB
Hyponatremia is the most common electrolyte disorder encountered in hospitalized patients, with SIAD being a leading cause of severe cases. The document discusses the clinical presentation of SIAD, the importance of careful sodium correction to avoid complications such as osmotic demyelination syndrome, and outlines current treatment guidelines. It emphasizes fluid restriction as the first-line therapy and explores second-line options, including tolvaptan and other agents, while addressing the risks associated with their use.
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