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Clinical reviews
STATE - OF - THE - ART REVIEW: ß - BLOCKADE IN CRITICAL ILLNESS
Marlies Ostermann, Daniel De Backer, Emilie Belley‑Cote, Maurizio Cecconi, Michelle S. Chew, Joanna C. Dionne, Steven M. Hollenberg, Stephan M. Jakob, Salmaan Kanji, Richard Leach, Mark J. McPhail, Xavier Monnet, Andrea Morelli, Mervyn Singer, Erika
PDF202618 pages3.0 MB
Critical illness is characterized by activation of the sympathetic nervous system, which is crucial for maintaining cardiovascular stability and organ perfusion. However, excessive adrenergic stimulation can lead to adverse outcomes such as tachyarrhythmias and organ dysfunction. This review examines the evidence for ß-blocker therapy in critically ill patients, highlighting established benefits in specific scenarios while acknowledging the ongoing debate regarding their overall efficacy.
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