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Clinical reviews
SEPTIC SHOCK: CURRENT OPINION IN CRITICAL CARE
Washington University
PDF20268 pages937 KB
Septic shock results from a dysregulated host response to infection and remains a significant cause of global morbidity and mortality. While standard care of septic shock remains protocolized due to improved outcomes with timely antibiotic and fluid administration, recent data have informed a more nuanced, individualized approach to sepsis management. Increasing evidence suggests that septic shock results from dynamic phases of immune dysregulation that may provide targets for precision therapy and data from large clinical trials have informed a complementary approach to fluid and vasopressor administration.
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