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Assoc Prof Joan Kalyango
The document introduces the definition of a hypothesis and distinguishes between null and alternative hypotheses, explaining one‑sided and two‑sided scenarios. It outlines the step‑by‑step process for conducting hypothesis tests, including selecting appropriate statistical tests. Sample size estimation is discussed with emphasis on study design, desired precision, and adjustments for clustering, loss to follow‑up, and non‑response. Practical examples illustrate calculations for descriptive studies and continuous outcomes. The material concludes with general considerations for equivalence and non‑inferiority trials.
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