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Clinical reviews
PRIMER Ulcerative colitis
Taku Kobayashi, Britta Siegmund, Catherine Le Berre, Shu Chen Wei, Marc Ferrante, Bo Shen, Charles N. Bernstein, Silvio Danese, Laurent Peyrin-Biroulet, Toshifumi Hibi
PDF202020 pages2.3 MB
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology affecting the colon and rectum. The document highlights the multifactorial nature of UC's pathogenesis, including genetic and environmental factors, and discusses the evolution of treatment strategies from symptomatic relief to achieving endoscopic and histological healing. Despite advancements in medical treatments, some patients still require surgical interventions. The document emphasizes the need for ongoing research into the disease's etiology and the development of novel therapies to improve patient outcomes.
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