Oxygen 2026

The Korman Respiratory Institute, Division of Pulmonary, Allergy and Critical Care, Department of Medicine at the Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA

The work traces the development of ventilatory support, beginning with the 1929 Drinker iron lung and the shift to positive‑pressure ventilation during the 1952 polio epidemic. It details how mechanical ventilation expanded in the 1960s‑1970s to treat all causes of respiratory failure. The later sections focus on lung transplantation, describing vascular anastomoses, bronchial artery considerations, immunosuppression, and ongoing complications. Throughout, the authors emphasize evidence‑based approaches and the importance of multidisciplinary care in critical care settings.