Maternal Sepsis

Dept of Obstetrics & Gynaecology, Mulago Specialised Women & Neonatal, Makerere University College of Health Sciences

Maternal sepsis is defined as life‑threatening organ dysfunction caused by infection during pregnancy, delivery, puerperium, or after abortion. The document outlines the use of the SOFA and qSOFA scores for early recognition and risk stratification. It emphasizes prompt administration of broad‑spectrum antibiotics within one hour, tailored to likely pathogens and local resistance patterns. Multidisciplinary care involving obstetrics, neonatology, anesthesiology, and critical care is recommended to optimize maternal and fetal outcomes. The guide also addresses prognosis, potential complications, and preventive measures to reduce delays in care.