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Guidelines & protocols
MANAGEMENT OF TRANSFUSION DEPENDENT THALASSAEMIA (TDT)
Thalassaemia International Federation
PDF2021351 pages3.2 MB
These guidelines provide comprehensive recommendations covering the genetic basis, pathophysiology, and diagnosis of both β‑ and α‑thalassaemia. They detail standards for blood transfusion practice, including haemovigilance, component specifications, transfusion thresholds, and management of adverse reactions. Iron overload assessment and therapy are addressed with evidence‑based recommendations. The document also outlines implementation strategies and levels of evidence for each recommendation. It is intended for clinicians managing transfusion‑dependent thalassaemia worldwide.
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