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Clinical reviews
Functional Dyspepsia
Mayo Clinic
PDF202611 pages3.9 MB
This clinical practice article addresses functional dyspepsia, a common and serious condition. It highlights the syndrome's potential for significant morbidity, including weight loss and food aversion, and its association with increased hospitalization and mortality risks. The article suggests that functional dyspepsia may comprise multiple distinct disorders, with a potential subgroup characterized by mucosal microinflammation. It also notes the overlap with other gastrointestinal syndromes like IBS and GERD, which exacerbates symptoms. The current lack of approved drugs means treatment is empirical, focusing on symptom management through acid suppressants, neuromodulators, and supportive nutritional and psychological care.
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