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Clinical reviews
DIAGNOSIS AND MANAGEMENT OF CENTRAL DIABETES INSIPIDUS IN ADULTS
Academic Department of Endocrinology, Beaumont Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland
PDF202215 pages3.1 MB
Central diabetes insipidus (CDI) is characterized by the inability to concentrate urine due to a deficiency of arginine vasopressin (AVP). The review discusses the diverse etiologies of CDI, including neoplastic, traumatic, or autoimmune causes. It highlights recent advancements in diagnostic techniques, particularly the copeptin assay, which enhances the accuracy of diagnosing hypotonic polyuria. The management strategies for CDI, including pharmacological treatments like dDAVP, are also explored.
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