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National Kidney Foundation, Inc.
The complement system is a crucial component of the innate immune response, playing a significant role in kidney diseases. This curriculum outlines the mechanisms of complement activation, its implications in renal pathology, and the emerging therapies targeting complement pathways. It emphasizes the necessity for nephrologists to understand complement diagnostics and the evolving landscape of anticomplement drugs for treating renal diseases. The document also reviews ongoing clinical trials and the potential for new biomarkers in assessing complement activity in kidney conditions.
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