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Weill Cornell Medical College
This fourth edition of Marino's The ICU Book provides an in-depth exploration of intensive care unit medicine. It details the mechanisms of the inflammatory response, including the role of neutrophils and the generation of reactive oxygen species. The book also addresses the concept of oxidant stress and its damaging effects on host cells. Furthermore, it discusses mechanical ventilation, including the management of air leaks and the phenomenon of intrinsic positive end-expiratory pressure (PEEP) and its adverse effects.
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